Medizinische Universität Graz Austria/Österreich - Forschungsportal - Medical University of Graz

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Gewählte Publikation:

SHR Neuro Krebs Kardio Lipid

Kurschel, S; Maier, R; Gellner, V; Eder, HG.
Chiari I malformation and intra-cranial hypertension:a case-based review.
Childs Nerv Syst. 2007; 23(8): 901-905. (- Case Report)
Web of Science PubMed FullText FullText_MUG


Autor/innen der Med Uni Graz:
Eder Hans
Gellner Verena
Kurschel Senta
Maier Richard

Dimensions Citations:

Plum Analytics:
OBJECTIVE: To present clinical and morphological findings before and after surgery in a child with Chairi I malformation (CMI) and intra-cranial hypertension (IH). The literature is reviewed and pathophysiologic factors are discussed. CLINICAL PRESENTATION: A 13-year-old obese boy with a 3-week history of headaches, neck pain, torticollis and progressive visual deterioration was admitted. Bi-lateral chronic papilloedema and decrease in visual acuity were found in the presence of a previously diagnosed CMI. INTERVENTION AND FOLLOW-UP: Intra-cranial pressure monitoring demonstrating increased pressure levels was followed by a sub-occipital decompression, C1 laminectomy and duroplasty. Post-operatively, the boy improved markedly, the 6 months follow-up opthalmological examination demonstrated resolution of papilloedema, but consecutive bi-lateral optic nerve atrophy. CONCLUSION: IH with progressive visual deterioration represents one of the varying clinical presentations of CMI and may be classified as a secondary form of idiopathic IH. Neuro-ophthalmological examination in all patients with CMI is recommended to identify the real incidence of this presentation. Altered CSF dynamics, venous hypertension and obesity as co-factors may be causative pathophysiologic factors.
Find related publications in this database (using NLM MeSH Indexing)
Arnold-Chiari Malformation - complications
Atrophy - complications
Child - complications
Humans - complications
Hypertension - complications
Intracranial Hypertension - etiology
Intracranial Pressure - physiology
Magnetic Resonance Imaging - physiology
Male - physiology
Neurosurgical Procedures - physiology
Obesity - complications
Optic Nerve Diseases - complications
Papilledema - complications
Vision Disorders - etiology
Visual Acuity - etiology

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